Effect of IRT5 probiotics on dry eye in the experimental dry eye mouse model
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چکیده
منابع مشابه
Therapeutic Effect of MK2 Inhibitor on Experimental Murine Dry Eye.
Purpose To investigate the role of mitogen-activated protein kinase-activated protein kinase-2 (MK2) in ocular surface damage of dry eye. Methods MK2 inhibition was performed in mice subjected to desiccating stress (DS) by topical application of MK2 inhibitor (MK2i) or vehicle eye drops. The total and phosphorylated MK2 in conjunctiva were detected by Western blot. The phenol red cotton test ...
متن کاملThe questionably dry eye.
This paper is concerned with the recognition of the dry eye when the clinical diagnosis is in doubt and other external eye diseases may be present. Papillary conjunctivitis is common to the dry eye as well as other pathological conditions and confuses the diagnosis. We have correlated the factors involved in the assessment for dryness. We have shown that particulate matter in the unstained tear...
متن کاملEvaluation of treatment for dry eye with 2-hydroxyestradiol using a dry eye rat model
PURPOSE 2-hydroxy estradiol (2-OHE2) is a catechol derivative of 17β -Estradiol (E2) and it is synthesized from E2 catalyzed by cytochrome P4501A1. Previous studies reported that 2-OHE2 is a physiologic antioxidant in lipoproteins, liver microsomes, and the brain. Catechol derivatives show an anti-inflammatory effect through the inhibition of prostaglandin endoperoxide synthase (PGS) activity. ...
متن کاملThe management of dry eye.
Dry eye disease (also called keratoconjunctivitis sicca) is a common condition, with a prevalence ranging from 8 to 34%, depending on the criteria used. It becomes more common with increasing age and affects more women than men. Artificial tears and ocular lubricants are considered the mainstay of treatment, and there is a very wide range of these products available. In England in 2014, over 6....
متن کاملDealing with dry eye.
Just as the name suggests, this condition makes the eyes feel dry, scratchy, and gritty. Other symptoms include burning, stinging, itching, pain, sensitivity to light, redness, blurry vision, and the feeling that there is a speck of dirt in the eye. There may also be a stringy discharge from the eyes. And though it may seem strange, dry eye can cause the eyes to water. "This can happen because ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2020
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0243176